Professional Publications

By Werner Doyle, M.D.

Original Reports

1. Budinger TF, Doyle WK, Levin VA, et al: Radiation necrosis of central nervous system studied by PET. J Nucl Med.1985;26:24.

2. Doyle WK, Budinger TF, Valk PE, et al.: Differentiation of cerebral radiation necrosis from tumor recurrence by [18F] FDG and 82Rb positron emission tomography. J Comput Assist Tomogr 1987;11:563-570.

3. Doyle W, Devinsky O, Perrine K, Dogali M: Decreased frequency of seizures after anticonvulsant holiday in medically refractory epilepsy, Seizure. 3(1):61-5, 1994 Mar.

4. Huang PP, Doyle W, Abbott IR, Atypical meningioma of the third ventricle in a 6-year-old boy. Neurosurgery 33:312-316, 1993.

5. Pacia SV, Devinsky O, Perrine K, Ravdin L, Luciano D, Vasquez B, Doyle W. Clinical Features of Neocortical Temporal Lobe Epilepsy, Ann Neurol, 1996;40:724-730

6. Pacia SV, Devinsky O, Perrine K, Luciano DJ, Vazquez B, Doyle WK, Dogali M, Abramson HS: Multiple subpial transections for intractable partial seizures:  Seizure outcome. J Epilepsy 10:86-91, 1997.

7. Schwartz TH, Devinsky O, Doyle WK, Perrine K, Preoperative predictors of anterior temporal language areas, J Neurosurg 89:962-970, 1998

8. Schwartz TH, Devinsky O, Doyle WK, Perrine K, Function-specific High-Probability “Nodes: Identified in Posterior Language Cortex, Epilepsia, 40(5):575-583, 1999

9. Devinsky O, Perrine K, Hirsch J, McMullen W, Pacia S, Doyle W, Relation of Cortical Language Distribution and Cognitive Function in Surgical Epilepsy Patients, Epilepsia, 41(4):400-404, 2000

10. Broderick PA, Pacia SV, Doyle WK, Devinsky O, Monoamine neurotransmitters in resected hippocampal subparcellations from neocortical and mesial temporal lobe epilepsy patients: In situ microvoltammetric studies, Brain Research 878 (2000) 48-63.

11. Sik A, Gulacsi A, Lai Y, Doyle W, Pacia S, Mody I, Freund T, Localization of A kinase anchoring protein AKAP79 in the human hippocampus, European Journal of Neuroscience, Vol 12, pp. 1155-1164, 2000.

12. Orbach D, Romanelli P, Devinsky O, Doyle W., Late seizure recurrence after multiple subpial transections. Epilepsia 2001 Sep;42(9):1130-3

13. Pacia SV, Doyle WK, Broderick PA, Biogenic amines in the human neocortex in patients with neocortical and mesial temporal lobe epilepsy: identification with in situ microvoltammetry, Brain Res 2001 Apr 27;899(1-2):106-11

14. Arle JE, Perrine K, Devinsky O, Doyle WK, Neural network analysis of preoperative variables and outcome in epilepsy surgery, J Neurosurg 1999 Jun;90(6):998-1002

15. Doyle WK, Low end interactive image-directed neurosurgery. Update on rudimentary augmented reality used in epilepsy surger,.Stud Health Technol Inform 1996;29:1-11.

16. Devinsky O, Frasca J, Pacia SV, Luciano DJ, Paraiso J, Doyle W, Ictus emeticus: further evidence of nondominant temporal involvement, Neurology 1995 Jun;45(6):1158-60.

17. Bekker AY, Kaufman B, Samir H, Doyle W, The use of dexmedetomidine infusion for awake craniotomy, Anesth Analg 2001 May;92(5):1251-3.

18. Perrine K, Devinsky O, Uysal S, Santschi C, Doyle WK., Cortical Mapping of Right Hemisphere Functions, Epilepsy Behav. 2000 Feb;1(1):7-16.

19. Kopell BH, Sala D, Doyle WK, Feldman DS, Wisoff JH, Weiner HL., Subfascial implantation of intrathecal baclofen pumps in children: technical note. Neurosurgery. 2001 Sep;49(3):753-6; discussion 756-7.

20. Hilz MJ, Devinsky O, Doyle W, Mauerer A, Dutsch M. Decrease of sympathetic cardiovascular modulation after temporal lobe epilepsy surgery. Brain. 2002 May;125(Pt 5):985-95.

21. Valk PE, Budinger TF, Levin VA, Silver P, Gutin PH, Doyle WK. PET of malignant cerebral tumors after interstitial brachytherapy. Demonstration of metabolic activity and correlation with clinical outcome.J Neurosurg. 1988 Dec;69(6):830-8.

22. Devinsky, O, Romanelli, P, Orbach D, Pacia, S, Doyle, W, Surgical Treatment of Multifocal Epilepsy Involving Eloquent Cortex, Epilepsia, 44(5): 718-723, 2003.

23. Dutsch M, Devinsky O, Doyle W, Marthol H, Hilz MJ, Cerebral autoregulation improves in epilepsy patients after temporal lobe surgery. J Neurol. 2004 Oct;251(10):1190-7

24. Prasad A, Pacia SV, Vazquez B, Doyle WK, Devinsky O.  Extent of ictal origin in mesial temporal sclerosis patients monitored with subdural intracranial electrodes predicts outcome. J Clin Neurophysiol. 2003 Jul-Aug;20(4):243-8.

25. Ard J, Doyle W, Bekker A, Awake craniotomy with dexmedetomidine in pediatric patients. J Neurosurg Anesthesiol. 2003 Jul;15(3):263-6.

26. Ard JL Jr, Bekker AY, Doyle WK. Dexmedetomidine in awake craniotomy: a technical note. Surg Neurol. 2005 Feb;63(2):114-6; discussion 116-7.

27. Bauman JA, Feoli E, Romanelli P, Doyle WK, Devinsky O, Weiner HL. Multistage epilepsy surgery: safety, efficacy, and utility of a novel approach in pediatric extratemporal epilepsy. Neurosurgery. 2005 Feb;56(2):318-34.

28. Heller SL, Heier LA, Watts R, Schwartz TH, Zelenko N, Doyle W, Devinsky O. Evidence of cerebral reorganization following perinatal stroke demonstrated with fMRI and DTI tractography. Clinical Imaging, Vol 29, Issue 4, July-August 2005, pages 283-287.

29. Burneo JG, Black L, Martin R, Devinsky O, Pacia S, Faught E, Vasquez B, Knowlton RC, Luciano D, Doyle W, Najjar S, Kuzniecky RI. Race/ethnicity, sex, and socioeconomic status as predictors of outcome after surgery for temporal lobe epilepsy.
Arch Neurol. 2006 Aug;63(8):1106-10.

30. Bauman JA, Ridgway EB, Devinsky O, Doyle WK. Subpectoral implantation of the vagus nerve stimulator. Neurosurgery. 2006 Apr;58(4 Suppl 2):ONS-322-5; discussion ONS-325-6.

31. Madhavan D, Mirowsli P, Ludvig N, Carlson C, Doyle W, Devinsky, O, Kuzniecky R, Effects of subdural application of lidocaine in patients with focal epilepsy, Epilepsy Research (2007).

32. Ludvig N, Kuzniecky RI, Baptiste SL, John JE, von Gizycki H, Doyle WK, Devinsky O. Epidural pentobarbital delivery can prevent locally induced neocortical seizures in rats: the prospect of transmeningeal pharmacotherapy for intractable focal epilepsy. Epilepsia. 2006 Nov;47(11):1792-802

33. Schevon CA, Carlson C, Zaroff CM, Weiner HJ, Doyle WK, Miles D, Lajoie J, Kuzniecky R, Pacia S, Vazquez B, Luciano D, Najjar S, Devinsky O. Pediatric language mapping: sensitivity of neurostimulation and Wada testing in epilepsy surgery. Epilepsia. 2007 Mar;48(3):539-45. Epub 2007 Feb 5

34. Alper K, Raghavan M, Isenhart R, Howard B, Doyle W, John R, Prichep L. Localizing epileptogenic regions in partial epilepsy using three-dimensional statistical parametric maps of background EEG source spectra. Neuroimage. 2008 Feb 1;39(3):1257-65. Epub 2007 Oct 4

Other Original Reports

1. Doyle WK, Rudimentary Virtual Reality in Neurosurgery: (Interactive Image-Directed Epilepsy Surgery), Journal of Medicine and Virtual Reality, 1:46-53, 1995

Proceedings of Meetings (Oral Presentations)

1. Budinger TF, Doyle WK, Levin VA, et al: Radiation necrosis of central nervous system studied by PET. Platform presentation: American Society of Nuclear Medicine, 1985 Annual Meeting.

2. Doyle W, McCarthy G, Spencer D, Luby M, MRI based hippocampal volumetry in epilepsy patients with surgical lesions. Platform presentation: American Epilepsy Society, 1992.

3. Thoracic Disc disease, Clinical presentation and surgical indications. American Association of Neurological Surgeons 1993 Annual Meeting.

4. Doyle WK, Interactive Image-Directed Epilepsy Surgery: (Rudimentary Virtual Reality in Neurosurgery), Medicine Meets Virtual Reality III, San Diego, Ca, 1995

5. Doyle WK, Low End Augmented Reality in Neurosurgery ( An Interactive Image Directed System Used in Epilepsy Surgery), Virtual Reality in Medicine and Developers' Expo, Cambridge, Mass, 1995

6. Doyle WK, Pacia S, Perrine K, Devinsky O, Preliminary experience with interactive image directed techniques for functional mapping and electrographic localization during epilepsy surgery, American Epilepsy Society Meeting, 1995.

7. Doyle WK, Interactive Image-Directed Epilepsy Surgery Using Magnetic Field Localizers, 19th Annual Post-Graduate Course, New York City, 1995

8. Doyle WK, Low-End Interactive Image-Directed Neurosurgery: Update on Rudimentary Virtual Reality Used in Epilepsy Surgery, Medicine Meets Virtual Reality IV, San Diego, Ca, 1996

9. Doyle WK, Devinsky O, Mogilner A, Multi-stage surgery for extratemporal epilepsy, American Epilepsy Society Meeting, 1998

10. Doyle, W, Complications and Outcomes in 1428 Surgical Procedures for Epilepsy. A Comprehensive Review of Contemporary Epilepsy Surgery from  One Epilepsy Center, American Society for Stereotactic and Functional Neurosurgery, May 18, 2003, New York, NY

11. Doyle, W,  Experience Using Frameless Navigation in 646 Epilepsy Surgery Cases, American Society for Stereotactic and Functional Neurosurgery, May 21, 2003, New York, NY

12. Doyle, W,, Complications and Outcome in 296 Vagus Nerve Stimulator Procedures for Epilepsy, American Society for Stereotactic and Functional Neurosurgery, May 21, 2003, New York, NY

13. Doyle, W, Epilepsy Surgery for Cortical Dysplasia (CD): Outcome and Efficacy of for Moderate to Severe CD, American Society for Stereotactic and Functional Neurosurgery, May 21, 2003, New York, NY

14. Doyle, W. Vagal Nerver Stimulation. Congress of Neurological Surgeons, Boston, MA, Oct 2004.

15. Sahin, NT, Pinker S, Cash S, Wang C, Devinsky O, Kuzniecky R, Doyle W, Halgrin E. Coherent Activity in Broca’s & Wernicke’s Areas in delta and dheta bands during noun and verb, as revealed through human intracranial EEG. ICCNS 2006, Boston, MA, (oral presentation) May 19 2006

Educationally Relevant Publications / Authored Book Chapters

1. Doyle W, Spencer D, Anterior Temporal Lobectomy in the treatment of Epilepsy. In Operative Neurosurgical Techniques (Third Edition), Edited by Schmedic and Sweet

2. Doyle WK, Interactive image-directed epilepsy surgery (Rudimentary virtual reality in neurosurgery), In Interactive Technology and the New Paradigm for Healthcare, Ed. by Satava RM, Morgan K, Sieburg HB, Matheus R, Christensen JP, Medicine Meets Virtual Reality Proceedings, IOS Press, 1995, P91-100.

3. Doyle W, Low End Augmented Reality in Neurosurgery (An Interactive Image-Directed System Used in Epilepsy Surgery), Virtual Reality in Medicine, pages 19-29, Official Proccedings 1995.

4. Doyle WK, Low End Interactive Image-Directed Neurosurgery (Update on Rudimentary Augmented Reality USed in Epilepsy Surgery), In Health Care in the Information Age, Ed. by H. Sieburg, S. Weghorst, and K. Morgan, IOS Press and Ohmsha, P1-11, 1996

5. Doyle W, Spencer D, Anterior Temporal Resections, Epilepsy: A Comprehensive Textbook, Edited by J. Engle, Jr. and T.A. Pedley. Lippincott-Raven Publishers, Chap 170, 1-11, 1997.

6. Doyle WK: Related topics: Neurosurgical management of chronic pain. In: Spivak JM, Di Cesare PE, Feldman SD, Koval KJ, Rokito AS, Zuckerman JD (eds): Orthopaedics: A Study Guide. New York: McGraw-Hill; 1999:939.

7. Doyle WK, Corpus Callosotomy in the Developmentally Diabled with Epilepsy. Epilepsy and Developmental Disabilities. Edited by Devinsky O and Westbrook LE. Butterworth Heinemann, 2002

Non-Print Materials

            Developed software for the BRW and Leksell stereotactic frame.
            Developed software for frameless computer assisted neurosurgical navigation.

            Developed frameless surgical navigation device used successfully in over 800 craniotomies.

            Design and development of devices and techniques for assisted neurosurgical navigation in epilepsy surgery

Published Medical Illustrations

1. Epstein FJ, Ozek M. The plated bayonet: a new instrument to facilitate surgery for intra-axial neoplasms of the spinal cord and brain stem. J Neurosurg 78:505-507, 1993.

2. Epstein FJ, Farmer J-P, Freed D, Adult intramedullary spinal cord ependymomas: the result of surgery in 38 patients. J Neurosurg 79:204-209, 1993.

3. Abbott, IR, Management of Congenital Spasticity in Children, The Practice of Neurosurgery, Edited by Tindall GT, Cooper PR, Barrow DL, Williams & Wilkins1996, Chapter 186: p 2805-2818.

4. Kopell BH, Sala D, Feldman DS, Wisoff JH, Weiner HL, Doyle WK, Subfascial Implantation of Intrathecal Baclofen Pumps in Children. Neurosurgery. 2001 Sep;49(3):753-6; discussion 756-7.

Abstracts

1. Doyle WK, Interactive Image Guided Neurosurgery in Epilepsy, American Association of Neurological Surgeons Annual Meeting 1995

2. Paraiso JO, Pacia SV, Doyle WK, Devinsky O, Sphenoidal versus anterior temporal scalp electrodes for the localization of temporal lobe seizures: Validation with simultaneous intracranial, sphenoidal, and scalp EEG, Neurology 45(Suppl 4), April 1995, p A456

3. Doyle WK, Comparison of interactive image-directed techniques and ultrasound for intraoperative localization of lesions in epilepsy surgery, Congress of Neurological Surgeons Annual Meeting 1995

4. Doyle WK, Interactive image-directed surgical techniques reduce craniotomy size for temporal lobectomies and improve placement of subdural strip electrodes, Congress of Neurological Surgeons Annual Meeting 1995

5. Doyle WK, Pacia S, Perrine K, Devinsky O, Preliminary experience with interactive image directed techniques for functional mapping and electrographic localization during epilepsy surgery, American Epilepsy Society Meeting, 1995; Abstract

6. Dahbour S, Pacia SV, Doyle WK, Devinsky O, Intracranial EEG Findings and Surgical Outcome in Neocortical Epilepsy, American Epilepsy Society Meeting, 1995; Abstract

7. Perrine K, Nelson PK, Doyle WK, Devinsky O, Language Mapping in Patients with Atypical Language Representation, American Epilepsy Society Meeting, 1995; Abstract

8. Ravdin LD, Perrine K, Pacia SV, Doyle WK, Devimsky O, Neuropsychological Findings in Patients with Documented Mesial and Neocortical Seizure Onsets, American Epilepsy Society Meeting, 1995; Abstract

9. Doyle W, Devinsky O, Perrine K, Pacia S, Vasquez B, Luciano D, Surgical Management of Post Traumatic Medically Refractory Epilepsy, Epilepsia 37, Suppl. 5, 1996, p 185.

10. Devinsky O, Perrine K, Doyle W, Factors Related to Atypical Language Localization, Epilepsia 37, Suppl. 5, 1996, p 130.

11. Quinn B, Conklin LS, Doyle W, Immunohistochemical Studies of Astrocytic Changes In Adult Cortical Epilepsy, Epilepsia 37, Suppl. 5, 1996, p 185.

12. Perrine K, McMullen WJ, Hirsh JA, Doyle W, Pacia S, Devinsky O, Neuropsychological Testing in Epilepsy Surgery Candidates With and Without a History of Traumatic Brain Injury, Epilepsia 37, Suppl. 5, 1996, p 185.

13. Doyle W, Devinsky O, Arle J, Pacia S, Correlation of MRI, Surface Video-EEG, and Invasive Monitoring in Patients Who Underwent Surgical Management for Medically Refractory Post-traumatic Epilepsy, American Association of Neurological Surgeons Annual Meeting 1997.

14. Arle J, Hadgar D, Pacia S, Doyle W, Outcome From Temporal or Frontal Lobectomy in Epileptic Patients With Cortical Dysplasia, American Association of Neurological Surgeons Annual Meeting 1997.

15. Arle J, Devinsky O, Perrine K, Doyle W, Outcome Prediction for Epilepsy Surgery Using Neural Network Analysis of Pre- and Intraoperative Data, XIIth Meeting of the World Society for Stereotactic and Functional Neurosurgery, 1997.

16. Doyle WK, Pacia SV, Devinsky O, Baptiste PJ, Rigg JL, Broderick PA, Preliminary Results Defining the Epileptic Substrate in Patients with Refractory Seizures Using in situ Microvoltametry.  Congress of Neurological Surgeons Annual Meeting, 1997.

17. Broderick PA, Jean-Batiste P, Rigg JL, Doyle WK, Pacia SV, Devinsky O, Monoamine Neurotransmitters in Human Neocortical Temporal-lobe Epilepsy (NTLE): Micro-voltammetric Studies, Epilepsia 28, Suppl 8, 1997, p 112.

18. Perrine K, Santschi C, Doyle WK, Pacia SV, Devinsky O, Correlates of Discordant WADA Memory Disparities, Epilepsia 28, Suppl 8, 1997, p 161.

19. Schwartz TH, Devinsky O, Rabinowitz D, Doyle WK, Perrine K, Stimulation Mapping of Wernike's Area: Localization, Variability, and Overlap Between Naming, Reading, and Arrest of Speech, Epilepsia 28, Suppl 8, 1997, p 217.

20. Doyle W, Devinsky O, Mogilner A, Multi-stage surgery for extratemporal epilepsy, Epilepsia 39, Suppliment 6, p 66, 1998.

21. Mogilner A, Osborn B, Doyle W, Risk of surgical infection for invasive subdural electrode monitoring, Epilepsia 39, Suppliment 6, p 91, 1998.

22. Pacia PV, Doyle WK, Devincky O, Jean-Batiste P, Broderick PA, Biochemical signatures in temporal lobe of patients with neocortical (NTLE) versus mesial temporal lobe epilepsy (MTLE): microvoltammetric detection, Epilepsia 39, Suppliment 6, p 117, 1998.

23. Broderick PA, Jean-Batiste P, Burns P, Pacia SV, Doyle WK, Serotonin deficiency within hippocampal subparcellations is present in patients with mesial temporal lobe epilepsy (MTLE) and is related to memory impairment as shown by Wada test, Epilepsia 39, Suppliment 6, p 117, 1998.

24. Mesad SM, Pacia SV, Devinsky O, Doyle W, Magnetoencephalography for extratemporal epilepsy, Epilepsia 39, Suppliment 6, p 209-210, 1998.

25. Perrine K, Pacia S, Doyle W, Mesad S, Devinsky O, Event-related desynchronization of depth electrode EEG during memory testing, Epilepsia 39, Suppliment 6, p 247-248, 1998.

26. Broderick PA, Jean-Baptiste P, Vuong AV, Pacia SV, Doyle WK, Devinsky O, Neurochemical signals from living neocortex of mesial temporal lobe epilepsy (MTLE) patients, studied by Broderick Probe lauric acid and stearic acid miniature sensors. Epilepsia Vol 40, Suppl 7, p 78-79, 1999.

27. Prasad A, Pacia SV, Devinsky O, Doyle WK. Extent of neocortical resection in anterior mesial temporal resection (AMTR) for mesial temporal sclerosis (MTS) influences aura but not seizure control. Epilepsia Vol 40, Suppl 7, p 60, 1999.

28. Weiner HL, Mogilner A, Doyle WK, Pacia SV, Wissof JH, Devinsky O. Multi-stage epilepsy surgery in children with extratemporal epilepsy due to cortical dysplasia. Epilepsia Vol 40, Suppl 7, p 125, 1999.

29. Doyle WK, Devinsky O, Pacia S, Luciano D, Vazquez B, Perrine K. Factors identifying successful reoperations for refractory epilepsy in patients presenting with failed epilepsy surgery. Epilepsia Vol 40, Suppl 7, p 216-217, 1999.

30. Bernadette E, Doyle W, Devinsky O, Pacia S, Vazquez B, Luciano D, Najjar S, Mesad S, Zupanc M, Silverberg A, Rivera E. Excellent outcome of surgical treratment for refractory epilepsy associated with extratemporal MRI identified disorders or cortical development. Epilepsia Vol 40, Suppl 7, p 217, 1999.

31. Broderick PA, Pacia SV, Doyle WK, Devinsky O, Serotonin (5HT) deficiency but high tryptophan (L-TP) concentrations within hippocampal subparcellations in patients with mesial temporal sclerosis (MTS). Epilepsia, Vol 41, Suppl. 7, 2000, p 91.

32. Pacia SV, Mangalmurti SS, Doyle WK, Devinsky O, Head trauma and temporal lobe epilepsy: mesial vs. neocortical seizures and surgical outcome. Epilepsia, Vol 41, Suppl. 7, 2000, p 143.

33. Doyle WK, Geller E, Devinsky O, Hubschmann O, Vagal nerve stimulation for epilpesy in setting of hypothalamic hamartoma. Epilepsia, Vol 41, Suppl. 7, 2000, p 147.

34. Romanelli P, Orbach D, Devinsky O, Doyle W, Long-term follow-up reveals late seizure recurrence following multiple subpial transections. Epilepsia, Vol 41, Suppl. 7, 2000, p 165.

35. Mesad SM, Raghavan M, Doyle W, Devinsky O, Utility of interictal spike quantification in predicting seizure onset zones and outcome. Epilepsia, Vol 42, Suppl. 7, 2001, p 39.

36. Avinash P, Pacia SV, Devinsky O, Doyle WK, Extent of ictal origin in mesial temporal lobe epilepsy patients monitored with subdural electrodes predicts surgical outcome. . Epilepsia, Vol 42, Suppl. 7, 2001, p 197.

37. Perrine K, Schwartz TH, Doyle WK, Devinsky O, Safety of cortical stimulation of multiple subdural grid contacts. Epilepsia, Vol 42, Suppl. 7, 2001, p 277.

38. Broderick PA, Pacia SV, Doyle WK, Devinsky O, In situ voltammetry with microelectrodes reliably distinguishes temporal lobe gray from white matter. Epilepsia, Vol 42, Suppl. 7, 2001, p 279.

39. Pacia SV, Doyle WK, Broderick PA, In situ microvoltrammetry of alveus from resected temporal lobe in patients with mesial (MTLE) and neocortical (NTLE) temporal lobe epilepsy. Epilepsia, Vol 42, Suppl. 7, 2001, p 279.

40. Ritaccio Al, Raghavan M, Devinsky O, Doyle W, Non-lesional parietal “plus” epilepsy: clinical and surgical aspects, American Epilepsy Society, Seattle WA, Dec. 9, 2002. Epilepsia 43 Suppl. 7:113 (Abst. 1.310)  , 2002

41. Raghavan M, Ritaccio A, Barr WB, Doyle W, Devinsky O, Plasticity of cortical language representation in temporal lobe epilepsy, American Epilepsy Society, Seattle WA, Dec. 10, 2002. Epilepsia 43 Suppl. 7:181 (Abst. 2.154) , 2002

42. Doyle W, Devinsky O, Contemporary epilepsy surgery experience: 1425 cases reviewed at one center, American Epilepsy Society, Seattle WA, Dec. 11, 2002. Epilepsia 43 Suppl. 7:321 (Abst. 3.213), 2002

43. Doyle, W, Complications and Outcomes in 1428 Surgical Procedures for Epilepsy. A Comprehensive Review of Contemporary Epilepsy Surgery from One Epilepsy Center, American Society for Stereotactic and Functional Neurosurgery, May 18, 2003, New York, NY

44. Doyle, W. Experience Using Frameless Navigation in 646 Epilepsy Surgery Cases, American Society for Stereotactic and Functional Neurosurgery, May 21, 2003, New York, NY

45. Doyle, W,, Complications and Outcome in 296 Vagus Nerve Stimulator Procedures for Epilepsy, American Society for Stereotactic and Functional Neurosurgery, May 21, 2003, New York, NY

46. Doyle, W, Epilepsy Surgery for Cortical Dysplasia (CD): Outcome and Efficacy of for Moderate to Severe CD, American Society for Stereotactic and Functional Neurosurgery, May 21, 2003, New York, NY

47. Doyle, W, Devinsky, O, Silverberg, A. Three-Stage Epilepsy Surgery. American Epilepsy Society, New Orleans, LA, Dec. 7, 2004

48. Bauman J, Devinsky O, Doyle W. Subpectoral Implantatin of Vagal Nerve Stimulator. American Epilepsy Society, New Orleans, LA, Dec. 7, 2004

49. Olgica Laban, William Barr, Werner Doyle, Souhel Najjar, Manoj Raghavan, False positive localization of language sites during electrical mapping near epileptic foci, Epilepsia 44 Suppl. 9:146 (Abst. 1.422), 2003

50. Alyson Silverberg, Werner K. Doyle, Complications and outcomes in 1428 surgical procedures for epilepsy, a comprehensive review of contemporary epilepsy surgery from one epilepsy center, Epilepsia 44 Suppl. 9:121 (Abst. 1.348), 2003

51. Werner K. Doyle, The emerging role of vagal nerve stimulation in epilepsy surgery, Epilepsia 44 Suppl. 9:322 (Abst. 2.430), 2003

52. A. Prasad, S.V. Pacia, O. Devinsky, W.K. Doyle, Extent of Ictal Origin in Mesial Temporal Lobe Epilepsy Patients Monitored with Subdural Electrodes Predicts Surgical Outcome, Epilepsia 42 Suppl. 7:197 (Abst. 2.305), 2001.

53. Catherine Schevon, MD, PhD1, Joshua Cappell, MD, PhD2, Werner Doyle, MD3, Howard Weiner, MD3, Robert Goodman, MD2., Ruben Kuzniecky, MD1 , and Ronald Emerson, MD2. Local Hypersynchrony in Intracranial EEG Recordings. American Epilepsy Society meeting, Washington D.C. December 2005.

54. Wang C, Ulbert I, Doyle w, Devinsky O, Kuzniecky R, Halgrin E, Neuronal responses during word processing in the human neocortex. Society for Neuroscience meeting, Washington D.C. Novenber 2005.

55. Chad Carlson, MD1, Catherine Schevon, MD, PhD1, Werner Doyle, MD3, Howard Weiner, MD3, Joshua Cappell, MD, PhD2, Ronald Emerson, MD2, Lawrence Hirsch, MD2, Robert Goodman, MD2, Orrin Devinsky, MD1, Steven Pacia, MD1 and Ruben Kuzniecky, MD1. Time-Frequency Analysis as an Adjunct to Intracranial EEG Interpretation. 2005 AES Abstracts

56. Catherine Schevon, MD, PhD1, Joshua Cappell, MD,PhD2, Werner Doyle, MD3, Howard Weiner, MD3, Robert Goodman, MD2, Ruben Kuzniecky, MD1 and Ronald Emerson, MD2. Local Hypersynchrony in Intracranial EEG Recordings. 2005 AES Abstracts

57. Chunmao Wang, Ph.D.1, Istvan Ulbert, Ph.D2, Werner K Doyle, M.D.1, Orrin Devinsky, M.D.1, Ruben Kuzniecky, M.D.1 and Eric Halgren, Ph.D. Spatio-temporal stages in word processing: intracranial-recorded potentials and current source density in the human frontal, temporal and occipital cortices. 2005 AES Abstracts

58. S S Cash1, I Ulbert2, O Devinsky3, E Bromfield4, J Madsen5, A Cole1, E Halgren6 and W Doyle. Laminar Microelectrode Recordings of Human Interictal Discharges in Neocortical Epilepsy Reveal Complex High-Frequency Oscillation Patterns. 2005 AES Abstracts.

59. Tariq A. Yousef, Steven V. Pacia, William Barr, Eric Cohen, Werner Doyle, Orrin Devinsky, Daniel Luciano, Blanca Vazquez, Daniel Miles, Souhel Najjar, and Ruben Kuzniecky. CLINICAL FEATURES OF PATIENTS WITH UNILATERAL MESIAL TEMPORAL SCLEROSIS (MTS) WITH PERSISTENT SEIZURES FOLLOWING ANTERO-MESIAL TEMPORAL RESECTION. Epilepsia 45 Suppl. 7 :88 (Abst. 1.221 ) , 2004

60. S.S. Cash, N. Meng, C. Melinosky, I. Ulbert, O. Devinsky, W. Doyle, A. Mehta, C. Wang, E. Bromfield, J. Madsen, and E. Halgren. Macro- and Microelectrode Recordings Show Complex Spatiotemporal Evolution of Focal Seizures in Human Epilepsy. 2006 American Epilepsy Society meeting, Chicago

61. E. Morrison, W.B. Barr, W. Doyle, C. Carlson, C.M. Zaroff, and O. Devinsky. Acute Language Changes Following Epilepsy Surgery. 2006 American Epilepsy Society meeting, Chicago.

62. Chad Carlson, Catherine Schevon, Jeff Stout, 1Siddhartha Nadkarni, Werner Doyle, Howard Weiner, 1Steven Pacia, ,Orrin Devinsky, and Ruben Kuzniecky. Magnetic Source Imaging for Pre-Surgical Lateralization of Refractory Epilepsy. 2006 American Epilepsy Society meeting, Chicago.

63. Sahin NT, Pinker S, Cash S, Wang Chunmao, Devinsky O, Kuzniecky R, Doyle W, Halgrin E. Coherent Activity in Broca’s & Wernike’s Areas in Delta Bands During Nounand Verb Inflection, as Revealed through Human Intracranial EEG,  International Concerence on Cognitive And Neuroal Systems (ICCNS) 2006, Boston MA, May 19, 2006.

64. Widdesswalsh, Peter, Geller, Eric, Doyle Werner, Devinsky Orrin , Bilateral ischemic optic neuropathy after subdural electrode placement for epilepsy surgery and treatment with erythropoietin, American Epilepsy Society, November 30 - December 4, 2007
in Philadelphia, PA.

65. Deepak Madhavan, Chad Carlson, Orrin Devinsky, Werner Doyle, Ruben Kuzniecky, Piotr Mirowski, Nandor Ludvig, Effects of the subdural application of lidocaine on EEG spiking in patients with focal epilepsy. December 4, 2007, American Epilepsy Society,  Philadelphia, PA.

66. Agnieszka Kokoszka, Alyson Silverberg , Chad Carlson, Josiane LaJoie, Mullin, Paul, Werner Doyle, Analysis of Revision Epilepsy Surgeries at a Major Academic Center, December 2, 2007, American Epilepsy Society,  Philadelphia, PA.

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